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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
15.45
Human Site:
S526
Identified Species:
21.25
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S526
T
E
P
V
V
A
A
S
A
R
P
A
G
D
S
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S526
T
E
P
V
V
A
A
S
A
R
P
A
G
D
S
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S647
T
E
P
V
V
A
A
S
A
R
P
A
G
D
S
Dog
Lupus familis
XP_543550
1017
111618
G526
T
E
P
V
A
T
T
G
A
R
P
A
G
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
A526
E
P
V
A
A
T
S
A
R
P
T
G
E
S
V
Rat
Rattus norvegicus
NP_001129232
1015
111665
A526
E
P
V
A
A
T
S
A
R
P
T
G
E
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
T526
S
K
P
S
A
E
P
T
A
A
S
I
K
P
T
Frog
Xenopus laevis
Q8QFR2
1013
112021
T526
V
E
L
V
G
N
N
T
K
P
A
E
E
T
A
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
E526
T
S
P
N
K
T
A
E
E
N
K
D
S
A
T
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
P526
Q
D
P
M
L
I
S
P
P
P
S
S
A
A
K
Fruit Fly
Dros. melanogaster
O17468
1047
113397
D523
R
R
Q
S
L
P
F
D
P
G
Q
S
N
E
L
Honey Bee
Apis mellifera
XP_001122939
838
91355
Y372
S
S
L
H
E
R
L
Y
G
K
P
L
V
Q
G
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
D469
K
Q
I
D
V
R
K
D
G
K
R
R
I
Q
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
G498
R
I
I
P
E
A
V
G
F
A
S
N
Q
D
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
R526
F
P
V
E
I
S
N
R
D
L
S
G
K
E
I
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
A374
D
G
S
L
L
F
V
A
S
L
D
S
S
I
T
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
S524
A
Q
L
V
G
A
S
S
T
K
P
V
Q
N
D
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
0
0
N.A.
N.A.
13.3
13.3
20
6.6
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
13.3
13.3
N.A.
N.A.
40
26.6
26.6
40
20
20
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
13.3
N.A.
0
0
26.6
P-Site Similarity:
N.A.
20
N.A.
20
40
53.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
12
24
30
24
18
30
12
6
24
6
12
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
6
0
6
0
0
0
12
6
0
6
6
0
30
6
% D
% Glu:
12
30
0
6
12
6
0
6
6
0
0
6
18
12
0
% E
% Phe:
6
0
0
0
0
6
6
0
6
0
0
0
0
0
0
% F
% Gly:
0
6
0
0
12
0
0
12
12
6
0
18
24
0
6
% G
% His:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
12
0
6
6
0
0
0
0
0
6
6
6
6
% I
% Lys:
6
6
0
0
6
0
6
0
6
18
6
0
12
0
6
% K
% Leu:
0
0
18
6
18
0
6
0
0
12
0
6
0
0
6
% L
% Met:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
0
6
12
0
0
6
0
6
6
6
6
% N
% Pro:
0
18
42
6
0
6
6
6
12
24
36
0
0
12
6
% P
% Gln:
6
12
6
0
0
0
0
0
0
0
6
0
12
12
0
% Q
% Arg:
12
6
0
0
0
12
0
6
12
24
6
6
0
0
0
% R
% Ser:
12
12
6
12
0
6
24
24
6
0
24
18
12
6
18
% S
% Thr:
30
0
0
0
0
24
6
12
6
0
12
0
0
6
24
% T
% Val:
6
0
18
36
24
0
12
0
0
0
0
6
6
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _